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Disease Profile

Parainfluenza virus type 3

Prevalence estimates on Rare Medical Network websites are calculated based on data available from numerous sources, including US and European government statistics, the NIH, Orphanet, and published epidemiologic studies. Rare disease population data is recognized to be highly variable, and based on a wide variety of source data and methodologies, so the prevalence data on this site should be assumed to be estimated and cannot be considered to be absolutely correct.


US Estimated

Europe Estimated

Age of onset





Autosomal dominant A pathogenic variant in only one gene copy in each cell is sufficient to cause an autosomal dominant disease.


Autosomal recessive Pathogenic variants in both copies of each gene of the chromosome are needed to cause an autosomal recessive disease and observe the mutant phenotype.


dominant X-linked dominant inheritance, sometimes referred to as X-linked dominance, is a mode of genetic inheritance by which a dominant gene is carried on the X chromosome.


recessive Pathogenic variants in both copies of a gene on the X chromosome cause an X-linked recessive disorder.


Mitochondrial or multigenic Mitochondrial genetic disorders can be caused by changes (mutations) in either the mitochondrial DNA or nuclear DNA that lead to dysfunction of the mitochondria and inadequate production of energy.


Multigenic or multifactor Inheritance involving many factors, of which at least one is genetic but none is of overwhelming importance, as in the causation of a disease by multiple genetic and environmental factors.


Not applicable


Other names (AKA)

Human parainfluenza virus type 3; PIV3


Viral infections


Parainfluenza virus type 3 is one of a group of common viruses known as human parainfluenza viruses (HPIV) that cause a variety of respiratory illnesses.[1] Symptoms usually develop between 2 and 7 days from the time of exposure and typically resolve in 7-10 days. [2][3] Symptoms may include fever, runny nose, and cough. HPIV-3 can also cause bronchiolitis, bronchitis, and pneumonia. Infants and young children are particularly susceptible to HPIV-3 infections, though older adults and those with a weakened immune system are also at risk for complications.[2][3] HPIVs are usually spread from an infected person to others through coughing, sneezing, and/or touching.[4] There is currently no vaccine to protect against parainfluenza virus infections. Most HPIV infections resolve on their own and do not require special treatment, though medical intervention may be necessary for severe breathing problems. [5][6][7] Most adults have antibodies against parainfluenza but can get repeat infections.[5]

Learn more

These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.

General Information

In-Depth Information

  • PubMed is a searchable database of medical literature and lists journal articles that discuss Parainfluenza virus type 3. Click on the link to view a sample search on this topic.


  1. Pringle, Craig. Parainfluenza Virus Infection. Merck Manual Professional Version. April, 2014; https://www.merckmanuals.com/professional/infectious-diseases/respiratory-viruses/parainfluenza-virus-infections. Accessed 8/30/2016.
  2. Human Parainfluenza Viruses (HPIVs) Symptoms and Illnesses. Centers for Disease Control and Prevention (CDC). August, 2015; https://www.cdc.gov/parainfluenza/about/symptoms.html. Accessed 8/30/2016.
  3. Parainfluenza Virus. Medscape. October 7, 2015; https://emedicine.medscape.com/article/224708-overview. Accessed 8/30/2016.
  4. Human Parainfluenza Viruses (HPIVs) Transmission. Centers for Disease Control and Prevention (CDC). August, 2015; https://www.cdc.gov/parainfluenza/about/transmission.html. Accessed 8/30/2016.
  5. Parainfluenza. MedlinePlus. August, 2014; https://medlineplus.gov/ency/article/001370.htm. Accessed 8/30/2016.
  6. Parainfluenza Viral Infections. American Academy of Pediatrics. November, 2015; https://www.healthychildren.org/English/health-issues/conditions/chest-lungs/Pages/Parainfluenza-Viral-Infections.aspx. Accessed 8/30/2016.
  7. Human Parainfluenza Viruses (HPIVs) Prevention and Treatment. Centers for Disease Control and Prevention (CDC). August, 2015; https://www.cdc.gov/parainfluenza/about/prevention-treatment.html. Accessed 8/30/2016.